Synthesis of superheavy element in terms of the fusion-evaporation reactions is evaluated and discussed. It is found that the reactions of and are relatively favorable with the maximum evaporation-residue cross sections of , , , and pb, respectively. However, may be difficult to be target because its spontaneous fission will bring about serious background in the experiment. Fusion probabilities for different target-projectile combinations leading to the formation of surperheavy nucleus are estimated with the “fusion-by-diffusion” model and presented as a function of the Coulomb parameter . Among the reactions , , , and , the reaction has the largest fusion probability. Synthesis of superheavy element is of essential importance for determining whether the magic proton shell should be at or at higher proton numbers . Therefore, the experiment to produce isotopes with in the fusion reactions is of great interest.