Living systems display organized, context-dependent dynamics through a restricted repertoire of persistent functional states. At mesoscopic scales, where biological motion is classical, dissipative, and noisy, such discreteness cannot be attributed to microscopic quantum effects alone. Here, we formulate a mesoscopic theory of functional closure for thermodynamically open episodes in which regulatory organization confines the dynamics to an approximately invariant informational class. Within a constrained open Hamilton-Jacobi framework, exact dissipative composability requires the complete irreversible realization of a biological act—including bulk, interfacial, regulatory, composite, and unresolved internal contributions—to admit an exhaustive, nonredundant thermodynamic partition. In an approximately isothermal regime, causal accumulation of the total irreversible power defines a unique positive dissipative-action scale, . This act-dependent scale sets the resolution of distinguishable functional realizations, while closure defines the domain on which a global additive action invariant can be constructed. If the nontrivial closure spectrum has a least positive action scale, its admissible values form an exact lattice. Quantization in biological dissipative-action units occurs only when this primitive closure scale saturates the independently constructed thermodynamic resolution, so that the spectrum is resolved in integer multiples of . Coherent functional modes are the closure-compatible, persistent, and action-resolved realizations of these discrete classes. The theory predicts clustering of completed trajectories in actionlike observables and separates state correlation, hidden dissipation, and information-geometric distinguishability from the exact composability of irreversible physical cost.