Realization of the conformal higher spin symmetry on the 4D massless field supermultiplets is given. The self-conjugated supermultiplets, including the linearized super Yang-Mills theory, are considered in some detail. Duality between nonunitary field-theoretical representations and the unitary doubleton-type representations of the 4D conformal algebra is formulated in terms of a Bogolyubov transform. The set of 4D massless fields of all spins is shown to form a representation of The results obtained are extended to the generalized superspace invariant under supersymmetries. A world line particle interpretation of the free higher spin theories in the invariant (super)space is given. Compatible with unitarity, free equations of motion in the invariant (super)space are formulated. A conjecture about the chain of (where CFT indicates conformal field theory) dualities in the higher spin gauge theories is proposed.