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Optimizing information transmission in optogenetic Wnt signaling

Olivier Witteveen ¹, Samuel J. Rosen ², Ryan S. Lach³, Maxwell Z. Wilson ^4,5,6,7,*, and Marianne Bauer ^1,†

¹Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Technische Universiteit Delft, Van der Maasweg 9, 2629 HZ Delft, The Netherlands
²Interdisciplinary Program in Quantitative Biosciences, University of California, Santa Barbara, California 93106, USA
³Integrated Biosciences, Inc., Redwood, California 94065, USA
⁴Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, California 93106, USA
⁵Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA
⁶Biomolecular Science and Engineering, University of California, Santa Barbara, California 93106, USA
⁷Center for BioEngineering, University of California, Santa Barbara, California 93106, USA

^*Contact author: mzw@ucsb.edu
^†Contact author: M.S.Bauer@tudelft.nl

Unifying theories in high-dimensional biophysics: approaches, challenges and opportunities

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npj Syst Biol Appl 12 43 (2026)

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Optimizing information transmission in optogenetic Wnt signaling

Unifying theories in high-dimensional biophysics: approaches, challenges and opportunities

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