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Cell migration dynamics explained by the coupling of mechanics with electrochemistry and pH regulation

Yizeng Li1,* and Sean X. Sun2,3,4,†

  • 1Department of Biomedical Engineering, Binghamton University, SUNY, Binghamton, New York 13902, USA
  • 2Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA
  • 3Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland 21218, USA
  • 4Center for Cell Dynamics, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA

  • *yli33@binghamton.edu
  • †ssun@jhu.edu

Hydrostatic pressure reduces the mechanosensitivity of cell migration

Ayuba Akinpelu, Abby Weaver, Farnaz Hemmati, Ethan Coker, Farshad Amiri, Chrystalla Stylianou, Ravi S. Vaghasiya, Matthew T. Garnett, Daniel Nweze, Maria Kalli, Symone Alexander, Triantafyllos Stylianopoulos, Yizeng Li, and Panagiotis Mistriotis

Sci. Adv. 12 eaed0981 (2026)

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