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  • Gallery of Fluid Motion
  • Open Access

Transition to turbulence past bioprosthetic aortic valves

Karoline-Marie Bornemann* and Dominik Obrist

  • ARTORG Center for Biomedical Engineering Research, University of Bern, Freiburgstrasse 3, 3010 Bern, Switzerland

  • *Contact author: karoline-marie.bornemann@unibe.ch

Phys. Rev. Fluids 10, 110504 – Published 20 November, 2025

DOI: https://doi.org/10.1103/czlh-94kv

Abstract

This paper is associated with a video winner of a 2024 American Physical Society's Division of Fluid Dynamics (DFD) Gallery of Fluid Motion Award for work presented at the DFD Gallery of Fluid Motion. The original video is available online at the Gallery of Fluid Motion, https://doi.org/10.1103/APS.DFD.2024.GFM.V2560348.

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References (18)

  1. A. Kheradvar, E. M. Groves, C. J. Goergen, S. H. Alavi, R. Tranquillo, C. A. Simmons, L. P. Dasi, K. J. Grande-Allen, M. R. Mofrad, A. Falahatpisheh, B. Griffith, F. Baaijens, S. H. Little, and S. Canic, Emerging trends in heart valve engineering: Part II. novel and standard technologies for aortic valve replacement, Ann. Biomed. Eng. 43, 844 (2015).
  2. K.-M. Bornemann and D. Obrist, Instability mechanisms initiating laminar-turbulent transition past bioprosthetic aortic valves, J. Fluid Mech. 985, A41 (2024).
  3. B. Becsek, L. Pietrasanta, and D. Obrist, Turbulent systolic flow downstream of a bioprosthetic aortic valve: Velocity spectra, wall shear stresses, and turbulent dissipation rates, Front. Physiol. 11, 577188 (2020).
  4. K.-M. Bornemann and D. Obrist, Leaflet fluttering changes laminar–turbulent transition mechanisms past bioprosthetic aortic valves, Phys. Fluids 37, 051911 (2025).
  5. J. H. Lee, L. N. Scotten, R. Hunt, T. G. Caranasos, J. P. Vavalle, and B. E. Griffith, Bioprosthetic aortic valve diameter and thickness are directly related to leaflet fluttering: Results from a combined experimental and computational modeling study, JTCVS Open 6, 60 (2021).
  6. Y. Chen and H. Luo, Pressure distribution over the leaflets and effect of bending stiffness on fluid–structure interaction of the aortic valve, J. Fluid Mech. 883, A52 (2020).
  7. E. L. Johnson, M. R. Rajanna, C. H. Yang, and M. C. Hsu, Effects of membrane and flexural stiffnesses on aortic valve dynamics: Identifying the mechanics of leaflet flutter in thinner biological tissues, Forces Mech. 6, 100053 (2022).
  8. T. Fringand, L. Mace, I. Cheylan, M. Lenoir, and J. Favier, Analysis of fluid–structure interaction mechanisms for a native aortic valve, patient-specific ozaki procedure, and a bioprosthetic valve, Ann. Biomed. Eng. 52, 3021 (2024).
  9. N. Broom, The stress/strain and fatigue behaviour of glutaraldehyde preserved heart-valve tissue, J. Biomech. 10, 707 (1977).
  10. N. Vyavahare, M. Ogle, F. J. Schoen, R. Zand, D. C. Gloeckner, M. Sacks, and R. J. Levy, Mechanisms of bioprosthetic heart valve failure: Fatigue causes collagen denaturation and glycosaminoglycan loss, J. Biomed. Mater. Res. 46, 44 (1999).
  11. A. Mirnajafi, B. Zubiate, and M. S. Sacks, Effects of cyclic flexural fatigue on porcine bioprosthetic heart valve heterograft biomaterials, J. Biomed. Mater. Res. Part A 94A, 205 (2010).
  12. H. Hatoum, A. Yousefi, S. Lilly, P. Maureira, J. Crestanello, and L. P. Dasi, An in vitro evaluation of turbulence after transcatheter aortic valve implantation, J. Thorac. Cardiovasc. Surg. 156, 1837 (2018).
  13. L. Ferrari and D. Obrist, Comparison of hemodynamic performance, three-dimensional flow fields, and turbulence levels for three different heart valves at three different hemodynamic conditions, Ann. Biomed. Eng. 52, 3196 (2024).
  14. R. Haj-Ali, G. Marom, S. B. Zekry, M. Rosenfeld, and E. Raanani, A general three-dimensional parametric geometry of the native aortic valve and root for biomechanical modeling, J. Biomech. 45, 2392 (2012).
  15. H. Reul, A. Vahlbruch, M. Giersiepen, T. Schmitz-Rode, V. Hirtz, and S. Effert, The geometry of the aortic root in health, at valve disease and after valve replacement, J. Biomech. 23, 181 (1990).
  16. R. Henniger, D. Obrist, and L. Kleiser, High-order accurate solution of the incompressible navier-stokes equations on massively parallel computers, J. Comput. Phys. 229, 3543 (2010).
  17. M. G. C. Nestola, B. Becsek, H. Zolfaghari, P. Zulian, D. D. Marinis, R. Krause, and D. Obrist, An immersed boundary method for fluid-structure interaction based on variational transfer, J. Comput. Phys. 398, 108884 (2019).
  18. J. Jeong, F. Hussain, W. Schoppa, and J. Kim, Coherent structures near the wall in a turbulent channel flow, J. Fluid Mech. 332, 185 (1997).

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