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Curvature in infectious disease network: A metric for vaccination and control

Sara Najem

Phys. Rev. E 114, 034312 – Published 24 September, 2026

DOI: https://doi.org/10.1103/c44l-89p7

Abstract

We investigate the geometric structure of evolving infectious-disease networks using a notion of node curvature, which is based on the heat-kernel expansion that naturally extends to edges. Applying this measure to networks reconstructed from infection counts whose degree and strength distributions transition toward a steady power-law, we observe a corresponding transition in curvature. We relate the latter to an underlying hyperbolic space and reveal a phase transition in the network's effective temperature. We further compare our curvature measure with existing definitions in the literature, demonstrating that all capture the transition consistently. Our results suggest that curvature provides a metric for characterizing structural changes in dynamic networks arising from infectious processes and identifies distinct phases where targeted vaccination strategies may be most effective, when used within a multimetric public health decision-making framework.

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References (38)

  1. M. Boguñá, I. Bonamassa, M. De Domenico, S. Havlin, D. Krioukov, and M. Ángeles Serrano, Network geometry, Nat. Rev. Phys. 3, 114 (2021).
  2. D. Brockmann and D. Helbing, The hidden geometry of complex, network-driven contagion phenomena, Science 342, 1337 (2013).
  3. C. Hens, U. Harush, S. Haber, R. Cohen, and B. Barzel, Spatiotemporal signal propagation in complex networks, Nat. Phys. 15, 403 (2019).
  4. F. Iannelli, A. Koher, D. Brockmann, P. Hövel, and I. M. Sokolov, Effective distances for epidemics spreading on complex networks, Phys. Rev. E 95, 012313 (2017).
  5. M. Boguñá, F. Papadopoulos, and D. Krioukov, Sustaining the internet with hyperbolic mapping, Nat. Commun. 1, 62 (2010).
  6. M. Boguñá, D. Krioukov, and K. C. Claffy, Navigability of complex networks, Nat. Phys. 5, 74 (2009).
  7. D. Krioukov, F. Papadopoulos, M. Kitsak, A. Vahdat, and M. Boguná, Hyperbolic geometry of complex networks, Phys. Rev. E 82, 036106 (2010).
  8. D. Krioukov, F. Papadopoulos, A. Vahdat, and M. Boguná, Curvature and temperature of complex networks, Phys. Rev. E 80, 035101(R) (2009).
  9. F. Papadopoulos, M. Kitsak, M. Ángeles Serrano, M. Boguná, and D. Krioukov, Popularity versus similarity in growing networks, Nature (London) 489, 537 (2012).
  10. M. Ángeles Serrano, D. Krioukov, and M. Boguná, Self-similarity of complex networks and hidden metric spaces, Phys. Rev. Lett. 100, 078701 (2008).
  11. A. Longhena, M. Guillemaud, and M. Chavez, Detecting local perturbations of networks in a latent hyperbolic embedding space, Chaos 34, 063117 (2024).
  12. X. Xia and C. de la Fuente-Nunez, Hyperbolic graph embeddings reveal the host-pathogen interactome, arXiv:2511.14669.
  13. Pawanesh, C. Sharma, and N. Sahni, Exploiting the geometry of heterogeneous networks: A case study of the Indian stock market, Soft Comput. 29, 4317 (2025).
  14. A. Muscoloni, J. M. Thomas, S. Ciucci, G. Bianconi, and C. V. Cannistraci, Machine learning meets complex networks via coalescent embedding in the hyperbolic space, Nat. Commun. 8, 1615 (2017).
  15. M. Fiedler, Algebraic connectivity of graphs, Czech. Math. J. 23, 298 (1973).
  16. Y. Ollivier, Ricci curvature of metric spaces, Compt. Rendus. Math. 345, 643 (2007).
  17. G. Bianconi, Higher-Order Networks (Cambridge University Press, Cambridge, 2021).
  18. K. Devriendt and R. Lambiotte, Discrete curvature on graphs from the effective resistance, J. Phys.: Complex. 3, 025008 (2022).
  19. K. Devriendt, A. Ottolini, and S. Steinerberger, Graph curvature via resistance distance, Discrete Appl. Math. 348, 68 (2024).
  20. L. Gao, X. Liu, Y. Liu, P. Wang, M. Deng, Q. Zhu, and H. Li, Measuring road network topology vulnerability by Ricci curvature, Physica A 527, 121071 (2019).
  21. D. Barros de Souza, J. T. S. Da Cunha, E. F. dos Santos, J. B. Correia, H. P. da Silva, J. L. de Lima Filho, J. Albuquerque, and F. A. N. Santos, Using discrete Ricci curvatures to infer COVID-19 epidemic network fragility and systemic risk, J. Stat. Mech. (2021) 053501.
  22. M. Pouryahya, J. Mathews, and A. Tannenbaum, Comparing three notions of discrete Ricci curvature on biological networks, arXiv:1712.02943. 
  23. A. Tannenbaum, C. Sander, L. Zhu, R. Sandhu, I. Kolesov, E. Reznik, Y. Senbabaoglu, and T. Georgiou, Ricci curvature and robustness of cancer networks, arXiv:1502.04512.
  24. H. Farooq, Y. Chen, T. T. Georgiou, A. Tannenbaum, and C. Lenglet, Network curvature as a hallmark of brain structural connectivity, Nat. Commun. 10, 4937 (2019).
  25. E. Estrada, Communicability cosine distance: Similarity and symmetry in graphs/networks, Computat. Appl. Math. 43, 49 (2024).
  26. S. Najem, D. Mrad, and M. Elsayed, Geometric features of higher-order networks via the spectral triplet, Commun. Phys. 9, 247 (2026).
  27. S. Najem, S. Monni, R. Hatoum, H. Sweidan, G. Faour, C. Abdallah, N. Ghosn, H. Hassan, and J. Touma, A framework for reconstructing transmission networks in infectious diseases, Appl. Netw. Sci. 7, 85 (2022).
  28. S. Meyer and L. Held, Power-law models for infectious disease spread, Ann. Appl. Stat. 8, 1612 (2014).
  29. F. Simini, M. C. González, A. Maritan, and A.-L. Barabási, A universal model for mobility and migration patterns, Nature (London) 484, 96 (2012).
  30. L. Held, M. Höhle, and M. Hofmann, A statistical framework for the analysis of multivariate infectious disease surveillance counts, Stat. Modell. 5, 187 (2005).
  31. M. Hoehle, S. Meyer, M. Paul, L. Held, H. Burkom, T. Correa, M. Hofmann, C. Lang, J. Manitz, S. Reichert, A. Riebler, D. S. Bove, M. Salmon, D. Schumacher, S. Steiner, M. Virtanen, W. Wei, V. Wimmer, and R Core Team, Surveillance: Temporal and spatio-temporal modeling and monitoring of epidemic phenomena, R package version 1.25.0, 2025, https://www.sciencedirect.com/bookseries/pure-and-applied-mathematics/vol/115/suppl/C.
  32. A. H. Chamseddine and A. Connes, The spectral action principle, Commun. Math. Phys. 186, 731 (1997).
  33. I. Chavel, Eigenvalues in Riemannian Geometry (Academic Press, New York, 1984), Vol. 115.
  34. J. J. Torres and G. Bianconi, Simplicial complexes: Higher-order spectral dimension and dynamics, J. Phys.: Complex. 1, 015002 (2020).
  35. A. P. Millán, H. Sun, L. Giambagli, R. Muolo, T. Carletti, J. J. Torres, F. Radicchi, J. Kurths, and G. Bianconi, Topology shapes dynamics of higher-order networks, Nat. Phys. 21, 353 (2025).
  36. A. P. Millán, J. G. Restrepo, J. J. Torres, and G. Bianconi, Geometry, topology and simplicial synchronization, in Higher-Order Systems (Springer, New York, 2022), pp. 269–299.
  37. C.-C. Ni, Graphriccicurvature: A Python library for computing Ollivier-Ricci and Forman-Ricci curvature on networks, 2019, Documentation available at https://graphriccicurvature.readthedocs.io/.
  38. https://www.dropbox.com/scl/fi/fb9ylt92rho7fiet4nc2z/ESUMOPHClearance.pdf?rlkey=kkr750fubkw9scbzd4oxifcna &st=ha55z0f9&dl=0

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