Transmitter-side device dependence is a longstanding yet implicit problem in quantum key distribution (QKD), in contrast to the thoroughly addressed measurement-side case. Quantum steering, which intrinsically distinguishes the roles of sender and receiver in entanglement certification, offers a natural route to lifting trust assumptions on the transmitter. Existing one-sided device-independent (1sDI) protocols that exploit quantum steering as the security resource typically operate in a tripartite architecture, whereas adapting them to a transmitter-receiver architecture can introduce a signaling loophole. Here we conceptually formalize the transmitter-device-independence on the basis of faithful quantum steering and propose a practical transmitter-device-independent (TDI) QKD protocol within the 1sDI trust model. The TDI scheme operationalizes the implicit no-signaling condition by enforcing a causal isolation between the input information and the transmitted quantum states, thereby eliminating the associated transmitter-side device vulnerabilities. In a proof-of-principle experiment, we validate the feasibility of the TDI protocol, achieving a key rate in the asymptotic limit of 410 bps over 27 km spool fiber. By delivering TDI security while retaining strong loss tolerance, our approach helps bridge the gap between security and practicality for real-world QKD deployments.

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• Optical quantum information processing
• Photonics
• Quantum cryptography
• Quantum optics
• Quantum protocols
• Devices