Atom interferometers represent a promising approach for gravitational wave detection in the decihertz frequency band, complementary to existing light-based detectors. The South Pole offers unique advantages for such experiments: exceptionally low seismic noise, established infrastructure for large scientific projects, and a location that strengthens gravitational wave source localization through global triangulation. Here we discuss the scientific case and practical considerations for deploying a long-baseline atom interferometer at the South Pole, which has the potential to expand the global network of gravitational wave detectors while enabling precision tests of fundamental physics.