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  • Letter
  • Open Access

Building rigid networks with prestress and selective pruning

Marco A. Galvani Cunha1,*, John C. Crocker2, and Andrea J. Liu1,3

  • 1Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
  • 2Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
  • 3Santa Fe Institute, Santa Fe, New Mexico 87501, USA

  • *Contact author: mgalvani@sas.upenn.edu
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Phys. Rev. Research 6, L042020 – Published 22 October, 2024

DOI: https://doi.org/10.1103/PhysRevResearch.6.L042020

Abstract

Biopolymer networks from the intracellular to tissue scale display high rigidity and tensile stress while having coordinations well below the normal threshold for mechanical rigidity. The elastic filaments in these networks are often severed by enzymes in a tension-inhibited manner. The effects of such pruning on the mechanics of prestressed networks have not been studied. We show that networks pruned by a tension-inhibited method remain rigid at much lower coordinations than randomly pruned ones. These findings suggest a possible reason for the repeated evolution of tension-inhibited filament-severing proteins.

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Phys. Rev. Research 6, L042020– Published 22 October, 2024
  • Received 22 December 2023
  • Accepted 26 September 2024
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Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.

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