An achiral, bent-core mesogen forms several tilted smectic liquid crystal phases, including a nonpolar, achiral de Vries smectic $A$ which transitions to a chiral, ferroelectric state in applied electric fields above a threshold. At lower temperature, a chiral, ferrielectric phase with a periodic, supermolecular modulation of the tilt azimuth, indicated by a Bragg peak in carbon-edge resonant soft x-ray scattering, is observed. The absence of a corresponding resonant umklapp peak identifies the superlayer structure as a twist-bend-like helix that is only weakly modulated by the smectic layering.

We study experimentally the origin of heterogeneous dynamics in strongly driven glass-forming systems. Thereto, we apply a well-defined force with a laser line trap on individual colloidal polystyrene probe particles seeded in an emulsion glass composed of droplets of the same size. Fluid and glass states can be probed. We monitor the trajectories of the probe and measure displacements and their distributions. Our experiments reveal intermittent dynamics around a depinning transition at a threshold force. For smaller forces, linear response connects mean displacement, and quiescent mean squared displacement. Mode coupling theory calculations rationalize the observations.

Autonomous implantable bioelectronics requires efficient radiating structures for data transfer and wireless powering. The radiation of body-implanted capsules is investigated to obtain the explicit radiation optima for $\mathbf{E}$- and $\mathbf{B}$-coupled sources of arbitrary dimensions and properties. The analysis uses the conservation-of-energy formulation within dispersive homogeneous and stratified canonical body models. The results reveal that the fundamental bounds exceed by far the efficiencies currently obtained by conventional designs. Finally, a practical realization of the optimal source based on a dielectric-loaded cylindrical-patch structure is presented. The radiation efficiency of the structure closely approaches the theoretical bounds and shows a fivefold improvement over existing systems.

Bootstrap, or $k$-core, percolation displays on the Bethe lattice a mixed first- and second-order phase transition with both a discontinuous order parameter and diverging critical fluctuations. I apply the recently introduced $M$-layer technique to study corrections to mean-field theory showing that at all orders in the loop expansion the problem is equivalent to a spinodal with quenched disorder. This implies that the mean-field hybrid transition does not survive in physical dimension. Nevertheless, its critical properties as an avoided transition make it a proxy of the avoided mode-coupling-theory critical point of supercooled liquids.

Permeability is one of the most fundamental transport properties in soft matter physics, material engineering, and nanofluidics. Here, we report by means of Langevin simulations of ideal penetrants in a nanoscale membrane made of a fixed lattice of attractive interaction sites, how the permeability can be massively tuned, even minimized or maximized, by tailoring the potential energy landscape for the diffusing penetrants, depending on the membrane attraction, topology, and density. Supported by limiting scaling theories we demonstrate that the observed nonmonotonic behavior and the occurrence of extreme values of the permeability is far from trivial and triggered by a strong anticorrelation and substantial (orders of magnitude) cancellation between penetrant partitioning and diffusivity, especially within dense and highly attractive membranes.

Simulations are used to study the steady shear rheology of dense suspensions of frictional particles exhibiting discontinuous shear thickening and shear jamming, in which finite-range cohesive interactions result in a yield stress. We develop a constitutive model that combines yielding behavior and shear thinning at low stress with the frictional shear thickening at high stresses, in good agreement with the simulation results. This work shows that there is a distinct difference between solids below the yield stress and in the shear-jammed state, as the two occur at widely separated stress levels, with an intermediate region of stress in which the material is flowable.

The microscopic kinetics of enzymes at the single-molecule level often deviate considerably from those expected from bulk biochemical experiments. Here, we propose a coarse-grained-model approach to bridge this gap, focusing on the unexpectedly slow bulk hydrolysis of crystalline cellulose by cellulase, which constitutes a major obstacle to mass production of biofuels and biochemicals. Building on our previous success in tracking the movements of single molecules of cellulase on crystalline cellulose, we develop a mathematical description of the collective motion and function of enzyme molecules hydrolyzing the surface of cellulose. Model simulations robustly explained the experimental findings at both the microscopic and macroscopic levels and revealed a hitherto-unknown mechanism causing a considerable slowdown of the reaction, which we call the crowding-out effect. The size of the cellulase molecule impacted significantly on the collective dynamics, whereas the rate of molecular motion on the surface did not.

Intermediate filaments are the least explored among the large cytoskeletal elements. We show here that they display conformational anomalies in narrow microfluidic channels. Their unusual behavior can be understood as the consequence of a previously undetected, large-scale helically curved superstructure. Confinement in a channel orders the otherwise soft, strongly fluctuating helical filaments and enhances their structural correlations, giving rise to experimentally detectable, strongly oscillating tangent correlation functions. We propose an explanation for the detected intrinsic curving phenomenon—an elastic shape instability that we call autocoiling. The mechanism involves self-induced filament buckling via a surface stress located at the outside of the cross section. The results agree with ultrastructural findings and rationalize for the commonly observed looped intermediate filament shapes. Beyond curvature, explaining the molecular origin of the detected helical torsion remains an interesting challenge.

We show by means of continuum theory and simulations that geometric percolation in uniaxial nematics of hard slender particles is fundamentally different from that in isotropic dispersions. In the nematic, percolation depends only very weakly on the density and is, in essence, determined by a distance criterion that defines connectivity. This unexpected finding has its roots in the nontrivial coupling between the density and the degree of orientational order that dictate the mean number of particle contacts. Clusters in the nematic are much longer than wide, suggesting the use of nematics for nanocomposites with strongly anisotropic transport properties.

We demonstrate a new form of capillary force experienced by neutrally buoyant spherical particles adsorbed simultaneously at both interfaces of a thin liquid film of spatially varying thickness. The force is proportional to the slope of the interface and the difference between the local contact angle and the equilibrium value, and exists even when the two bounding interfaces have zero curvature. We derive the expression for the force, which when balanced against the hydrodynamic drag gives the trajectory of the particle. The measured trajectories for spherical particles of varying diameters in thin films compare well with predictions.

We investigate the dynamics of a dilute suspension of hydrodynamically interacting motile or immotile stress-generating swimmers or particles as they invade a surrounding viscous fluid. Colonies of aligned pusher particles are shown to elongate in the direction of particle orientation and undergo a cascade of transverse concentration instabilities, governed at small times by an equation that also describes the Saffman-Taylor instability in a Hele-Shaw cell, or the Rayleigh-Taylor instability in a two-dimensional flow through a porous medium. Thin sheets of aligned pusher particles are always unstable, while sheets of aligned puller particles can either be stable (immotile particles), or unstable (motile particles) with a growth rate that is nonmonotonic in the force dipole strength. We also prove a surprising “no-flow theorem”: a distribution initially isotropic in orientation loses isotropy immediately but in such a way that results in no fluid flow everywhere and for all time.

A salient feature of skeletal muscles is their ability to take up an applied slack in a microsecond timescale. Behind this fast adaptation is a collective folding in a bundle of elastically interacting bistable elements. Since this interaction has a long-range character, the behavior of the system in force and length controlled ensembles is different; in particular, it can have two distinct order-disorder–type critical points. We show that the account of the disregistry between myosin and actin filaments places the elementary force-producing units of skeletal muscles close to both such critical points. The ensuing “double criticality” contributes to the system’s ability to perform robustly and suggests that the disregistry is functional.

During the spreading of epithelial tissues, the advancing tissue front often develops fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven fluids suggests that epithelial fingers could arise from an interfacial instability. However, the existence and physical mechanism of such a putative instability remain unclear. Here, based on an active polar fluid model for epithelial spreading, we analytically predict a generic instability of the tissue front. On the one hand, active cellular traction forces impose a velocity gradient that leads to an accelerated front, which is, thus, unstable to long-wavelength perturbations. On the other hand, contractile intercellular stresses typically dominate over surface tension in stabilizing short-wavelength perturbations. Finally, the finite range of hydrodynamic interactions in the tissue selects a wavelength for the fingering pattern, which is, thus, given by the smallest between the tissue size and the hydrodynamic screening length. Overall, we show that spreading epithelia experience an active fingering instability based on a simple kinematic mechanism. Moreover, our results underscore the crucial role of long-range hydrodynamic interactions in the dynamics of tissue morphology.

The precipitation of a glass forming solute from solution is modeled using a lattice model previously introduced to study dissolution kinetics of amorphous materials. The model includes the enhancement of kinetics at the surface of a glass in contact with a plasticizing solvent. We demonstrate that precipitation can produce a glass substantially more stable than that produced by very long time annealing of the bulk glass former. The energy of these ultrastable amorphous precipitates is found to be dominated by residual solvent rather than high energy glass configurations.

The hydrodynamic theory of polar liquid crystals is widely used to describe biological active fluids as well as passive molecular materials. Depending on the “shear-alignment parameter”, in passive or weakly active polar fluids under external shear, the polar order parameter $\mathbf{p}$ is either inclined to the flow at a fixed (Leslie) angle, or rotates continuously. Here, we study the role of an additional “shear-elongation parameter” that has been neglected in the recent literature and causes $|\mathbf{p}|$ to change under flow. We show that this effect can give rise to a shear-induced first-order phase transition from isotropic to polar, and significantly change the rheological properties of both active and passive polar fluids.

While coalescence is ultimately the most drastic destabilization process in foams, its underlying processes are still unclear. To better understand them, we track individual coalescence events in two-dimensional foams at controlled capillary pressure. We obtain statistical information revealing the influence of the different parameters which have been previously proposed to explain coalescence. Our main conclusion is that coalescence probability is simply proportional to the area of the thin film separating two bubbles, suggesting that coalescence is mostly stochastic.

In nonexcitable cells, global ${\mathrm{Ca}}^{2+}$ spikes emerge from the collective dynamics of clusters of ${\mathrm{Ca}}^{2+}$ channels that are coupled by diffusion. Current modeling approaches have opposed stochastic descriptions of these systems to purely deterministic models, while both paradoxically appear compatible with experimental data. Combining fully stochastic simulations and mean-field analyses, we demonstrate that these two approaches can be reconciled. Our fully stochastic model generates spike sequences that can be seen as noise-perturbed oscillations of deterministic origin, while displaying statistical properties in agreement with experimental data. These underlying deterministic oscillations arise from a phenomenological spike nucleation mechanism.

The cellular uptake of nanoparticles or viruses requires that the gain of adhesion energy overcomes the cost of plasma membrane bending. It is well known that this leads to a minimal particle size for uptake. Using a simple deterministic theory for this process, we first show that, for the same radius and volume, cylindrical particles should be taken up faster than spherical particles, both for normal and parallel orientations. We then address stochastic effects, which are expected to be relevant due to small system size, and show that, now, spherical particles can have a faster uptake because the mean first passage time profits from the multiplicative noise induced by the spherical geometry. We conclude that stochastic effects are strongly geometry dependent and may favor spherical shapes during adhesion-driven particle uptake.