We report a ferromagnetic-like anomalous Hall resistivity and giant isotropic negative magnetoresistance (NMR) in the antiferromagnetic half-Heusler compound DyPdBi. The FM-like anomalous Hall resistivity appears exclusively in antiferromagnetic state II, yet it is not coupled to magnetization, indicating a Berry-curvature origin. Additionally, the magnetoresistance drops by 98%, and the NMR persists above the Néel temperature ($T_{\mathrm{N}}$). We attribute both phenomena to a half-topological-semimetal (HTS) state, similar to that proposed for TbPdBi, arising from weak band inversion strength (BIS). This state enhances spin polarization, reducing Berry curvature cancellation and strengthening anomalous Hall effect (AHE). These observations suggest that weak BIS in the RPdBi family gives rise to an HTS that potentially interacts with exotic spin states, producing an exceptionally large AHE. This study highlights a strategy for engineering large AHE in half-Heusler antiferromagnets, and advances the further topological spintronics design.

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• Anomalous Hall effect
• Antiferromagnets
• Half-Heusler alloy
• Semimetals