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Phys. Rev. Lett. (1)

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Evolutionary Benefits of Fitness-Dependent Mutation Rates

Andrew G. T. Pyo ¹, Qiwei Yu ², Julia Merkenschlager ³, and Ned S. Wingreen ^2,4,*

¹Department of Physics, Princeton University, Princeton, New Jersey 08544, USA
²Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA
³Department of Immunology, Harvard Medical School, Boston, Massachusetts 02115, USA
⁴Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA

^*Contact author: wingreen@princeton.edu

Evolutionary Benefits of Fitness-Dependent Mutation Rates

Andrew G. T. Pyo, Qiwei Yu, Julia Merkenschlager, and Ned S. Wingreen

Phys. Rev. Lett. 135 048402 (2025)

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