We introduce a variational Monte Carlo framework that combines neural-network quantum states with the Lorentz integral transform technique to compute the dynamical properties of self-bound quantum many-body systems in continuous Hilbert spaces. While broadly applicable to various quantum systems, including atoms and molecules, in this initial application we focus on the photoabsorption cross section of light nuclei, where benchmarks against numerically exact techniques are available. Our accurate theoretical predictions are complemented by robust uncertainty quantification, enabling meaningful comparisons with experiments. We demonstrate that a relatively simple nuclear Hamiltonian—based on a leading-order pionless EFT expansion and known to accurately reproduce ground-state energies of nuclei with $A\le 40$—also provides a reliable description of the photoabsorption cross section.

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• Few-body systems
• Lepton induced nuclear reactions
• Nuclear many-body theory
• Nuclear reactions
• Photonuclear reactions
• Ab initio calculations
• Monte Carlo methods
• Quantum Monte Carlo