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Cooling Mechanism Controls Motility-Induced Phase Separation in Inertial Active Liquids
Phys. Rev. Lett. 136, 188301 – Published 8 May, 2026
DOI: https://doi.org/10.1103/mbrl-v75b
Abstract
Motility-induced phase separation (MIPS) is a central collective phenomenon in active matter, theoretically established in the overdamped regime. We discover that the dynamical origin of MIPS is fundamentally altered by inertia, which induces a cooling mechanism absent in overdamped active matter. This conclusion is supported by an active variant of the direct simulation Monte Carlo method and by a kinetic theory for inertial self-propelled hard spheres derived from the microscopic dynamics. In contrast to the overdamped case, both analyses demonstrate that inertial MIPS can occur even without impenetrability, as it originates from a density-dependent cooling mechanism due to the coupling of density, orientation, and temperature. This mechanism emerges from the competition between activity and a density-dependent collision rate arising from spatial correlations between colliding particles. These findings open a pathway to fundamentally connect inertial active matter with granular physics.
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References (87)
- M. C. Marchetti, J. F. Joanny, S. Ramaswamy, T. B. Liverpool, J. Prost, M. Rao, and R. A. Simha, Hydrodynamics of soft active matter, Rev. Mod. Phys. 85, 1143 (2013).
- J. Elgeti, R. G. Winkler, and G. Gompper, Physics of microswimmers—Single particle motion and collective behavior: A review, Rep. Prog. Phys. 78, 056601 (2015).
- C. Bechinger, R. Di Leonardo, H. Löwen, C. Reichhardt, G. Volpe, and G. Volpe, Active particles in complex and crowded environments, Rev. Mod. Phys. 88, 045006 (2016).
- R. G. Winkler and G. Gompper, The physics of active polymers and filaments, J. Chem. Phys. 153, 040901 (2020).
- B. Nath, L. Caprini, C. Maggi, A. Zizzari, V. Arima, I. Viola, R. Di Leonardo, and A. Puglisi, A microfluidic method for passive trapping of sperms in microstructures, Lab Chip 23, 773 (2023).
- R. Di Leonardo, L. Angelani, D. Dell’Arciprete, G. Ruocco, V. Iebba, S. Schippa, M. P. Conte, F. Mecarini, F. De Angelis, and E. Di Fabrizio, Bacterial ratchet motors, Proc. Natl. Acad. Sci. U.S.A. 107, 9541 (2010).
- J. Arlt, V. A. Martinez, A. Dawson, T. Pilizota, and W. C. Poon, Painting with light-powered bacteria, Nat. Commun. 9, 768 (2018).
- I. Buttinoni, J. Bialké, F. Kümmel, H. Löwen, C. Bechinger, and T. Speck, Dynamical clustering and phase separation in suspensions of self-propelled colloidal particles, Phys. Rev. Lett. 110, 238301 (2013).
- A. Bricard, J.-B. Caussin, N. Desreumaux, O. Dauchot, and D. Bartolo, Emergence of macroscopic directed motion in populations of motile colloids, Nature (London) 503, 95 (2013).
- A. Cavagna and I. Giardina, Bird flocks as condensed matter, Annu. Rev. Condens. Matter Phys. 5, 183 (2014).
- M. Moussaïd, N. Perozo, S. Garnier, D. Helbing, and G. Theraulaz, The walking behaviour of pedestrian social groups and its impact on crowd dynamics, PLoS One 5, e10047 (2010).
- M. Leyman, F. Ogemark, J. Wehr, and G. Volpe, Tuning phototactic robots with sensorial delays, Phys. Rev. E 98, 052606 (2018).
- M. Agrawal and S. C. Glotzer, Scale-free, programmable design of morphable chain loops of kilobots and colloidal motors, Proc. Natl. Acad. Sci. U.S.A. 117, 8700 (2020).
- G. Vásárhelyi, C. Virágh, G. Somorjai, T. Nepusz, A. E. Eiben, and T. Vicsek, Optimized flocking of autonomous drones in confined environments, Sci. Rob. 3, eaat3536 (2018).
- J. O’Byrne, Y. Kafri, J. Tailleur, and F. van Wijland, Time irreversibility in active matter, from micro to macro, Nat. Rev. Phys. 4, 167 (2022).
- M. E. Cates and J. Tailleur, Motility-induced phase separation, Annu. Rev. Condens. Matter Phys. 6, 219 (2015).
- G. Gonnella, D. Marenduzzo, A. Suma, and A. Tiribocchi, Motility-induced phase separation and coarsening in active matter, C.R. Phys. 16, 316 (2015).
- J. Bialké, T. Speck, and H. Löwen, Active colloidal suspensions: Clustering and phase behavior, J. Non-Cryst. Solids 407, 367 (2015).
- Y. Fily and M. C. Marchetti, Athermal phase separation of self-propelled particles with no alignment, Phys. Rev. Lett. 108, 235702 (2012).
- G. S. Redner, M. F. Hagan, and A. Baskaran, Structure and dynamics of a phase-separating active colloidal fluid, Phys. Rev. Lett. 110, 055701 (2013).
- D. Levis, J. Codina, and I. Pagonabarraga, Active Brownian equation of state: Metastability and phase coexistence, Soft Matter 13, 8113 (2017).
- P. Digregorio, D. Levis, A. Suma, L. F. Cugliandolo, G. Gonnella, and I. Pagonabarraga, Full phase diagram of active brownian disks: From melting to motility-induced phase separation, Phys. Rev. Lett. 121, 098003 (2018).
- S. Hermann, D. de Las Heras, and M. Schmidt, Non-negative interfacial tension in phase-separated active Brownian particles, Phys. Rev. Lett. 123, 268002 (2019).
- T. Speck, Collective behavior of active Brownian particles: From microscopic clustering to macroscopic phase separation, Eur. Phys. J. Special Topics 225, 2287 (2016).
- J. U. Klamser, S. C. Kapfer, and W. Krauth, Thermodynamic phases in two-dimensional active matter, Nat. Commun. 9, 5045 (2018).
- L. Caprini, U. Marini Bettolo Marconi, and A. Puglisi, Spontaneous velocity alignment in motility-induced phase separation, Phys. Rev. Lett. 124, 078001 (2020).
- S. Bröker, J. Bickmann, M. Te Vrugt, M. E. Cates, and R. Wittkowski, Orientation-dependent propulsion of active brownian spheres: From self-advection to programmable cluster shapes, Phys. Rev. Lett. 131, 168203 (2023).
- R. F.-Q. García, E. Chacón, P. Tarazona, and C. Valeriani, Dynamics and rupture of doped motility induced phase separation, Soft Matter 21, 5413 (2025).
- R. Wittmann, C. Maggi, A. Sharma, A. Scacchi, J. M. Brader, and U. M. B. Marconi, Effective equilibrium states in the colored-noise model for active matter I. Pairwise forces in the fox and unified colored noise approximations, J. Stat. Mech. (2017) P113207.
- A. P. Solon, J. Stenhammar, R. Wittkowski, M. Kardar, Y. Kafri, M. E. Cates, and J. Tailleur, Pressure and phase equilibria in interacting active Brownian spheres, Phys. Rev. Lett. 114, 198301 (2015).
- A. K. Omar, H. Row, S. A. Mallory, and J. F. Brady, Mechanical theory of nonequilibrium coexistence and motility-induced phase separation, Proc. Natl. Acad. Sci. U.S.A. 120, e2219900120 (2023).
- R. Soto, M. Pinto, and R. Brito, Kinetic theory of motility induced phase separation for active Brownian particles, Phys. Rev. Lett. 132, 208301 (2024).
- H. Löwen, Inertial effects of self-propelled particles: From active Brownian to active Langevin motion, J. Chem. Phys. 152, 040901 (2020).
- P. Baconnier, D. Shohat, C. H. López, C. Coulais, V. Démery, G. Düring, and O. Dauchot, Selective and collective actuation in active solids, Nat. Phys. 18, 1234 (2022).
- F. Siebers, A. Jayaram, P. Blümler, and T. Speck, Exploiting compositional disorder in collectives of light-driven circle walkers, Sci. Adv. 9, eadf5443 (2023).
- K. Engbring, D. Boriskovsky, Y. Roichman, and B. Lindner, A nonlinear fluctuation-dissipation test for Markovian systems, Phys. Rev. X 13, 021034 (2023).
- M. Casiulis, E. Arbel, Y. Lahini, S. Martiniani, N. Oppenheimer, and M. Y. B. Zion, A geometric condition for robot-swarm cohesion and cluster-flock transition, Proc. Natl. Acad. Sci. U.S.A. 122, e2502211122 (2025).
- I. S. Aranson, D. Volfson, and L. S. Tsimring, Swirling motion in a system of vibrated elongated particles, Phys. Rev. E 75, 051301 (2007).
- A. Kudrolli, G. Lumay, D. Volfson, and L. S. Tsimring, Swarming and swirling in self-propelled polar granular rods, Phys. Rev. Lett. 100, 058001 (2008).
- J. Deseigne, O. Dauchot, and H. Chaté, Collective motion of vibrated polar disks, Phys. Rev. Lett. 105, 098001 (2010).
- N. Kumar, H. Soni, S. Ramaswamy, and A. Sood, Flocking at a distance in active granular matter, Nat. Commun. 5, 4688 (2014).
- N. Koumakis, A. Gnoli, C. Maggi, A. Puglisi, and R. Di Leonardo, Mechanism of self-propulsion in 3D-printed active granular particles, New J. Phys. 18, 113046 (2016).
- A. P. Antonov, L. Caprini, A. Ldov, C. Scholz, and H. Löwen, Inertial active matter with coulomb friction, Phys. Rev. Lett. 133, 198301 (2024).
- C. Scholz, M. Engel, and T. Pöschel, Rotating robots move collectively and self-organize, Nat. Commun. 9, 931 (2018).
- M. Workamp, G. Ramirez, K. E. Daniels, and J. A. Dijksman, Symmetry-reversals in chiral active matter, Soft Matter 14, 5572 (2018).
- M. López-Castaño, J. F. González-Saavedra, A. Rodríguez-Rivas, E. Abad, S. B. Yuste, and F. Vega Reyes, Pseudo-two-dimensional dynamics in a system of macroscopic rolling spheres, Phys. Rev. E 103, 042903 (2021).
- M. A. López-Castaño, A. Marquez Seco, A. Marquez Seco, A. Rodriguez-Rivas, and F. V. Reyes, Chirality transitions in a system of active flat spinners, Phys. Rev. Res. 4, 033230 (2022).
- J. Rabault, R. A. Fauli, and A. Carlson, Curving to fly: Synthetic adaptation unveils optimal flight performance of whirling fruits, Phys. Rev. Lett. 122, 024501 (2019).
- H. Mukundarajan, T. C. Bardon, D. H. Kim, and M. Prakash, Surface tension dominates insect flight on fluid interfaces, J. Exp. Biol. 219, 752 (2016).
- S. C. Takatori and J. F. Brady, Inertial effects on the stress generation of active fluids, Phys. Rev. Fluids 2, 094305 (2017).
- C. Scholz, S. Jahanshahi, A. Ldov, and H. Löwen, Inertial delay of self-propelled particles, Nat. Commun. 9, 5156 (2018).
- M. Leoni, M. Paoluzzi, S. Eldeen, A. Estrada, L. Nguyen, M. Alexandrescu, K. Sherb, and W. W. Ahmed, Surfing and crawling macroscopic active particles under strong confinement: Inertial dynamics, Phys. Rev. Res. 2, 043299 (2020).
- L. Caprini and U. Marini Bettolo Marconi, Inertial self-propelled particles, J. Chem. Phys. 154, 024902 (2021).
- G. P. Nguyen, R. Wittmann, and H. Löwen, Active ornstein–uhlenbeck model for self-propelled particles with inertia, J. Phys. USSR 34, 035101 (2021).
- S. De Karmakar, A. Chugh, and R. Ganesh, Collective behavior of soft self-propelled disks with rotational inertia, Sci. Rep. 12, 22563 (2022).
- N. P. Kryuchkov, A. D. Nasyrov, K. D. Gursky, and S. O. Yurchenko, Inertia changes evolution of motility-induced phase separation in active matter across particle activity, Phys. Rev. E 107, 044601 (2023).
- A. Deblais, T. Barois, T. Guerin, P.-H. Delville, R. Vaudaine, J. S. Lintuvuori, J.-F. Boudet, J.-C. Baret, and H. Kellay, Boundaries control collective dynamics of inertial self-propelled robots, Phys. Rev. Lett. 120, 188002 (2018).
- A. P. Antonov, M. Musacchio, H. Löwen, and L. Caprini, Self-sustained frictional cooling in active matter, Nat. Commun. 16, 7235 (2025).
- L. Caprini, D. Breoni, A. Ldov, C. Scholz, and H. Löwen, Dynamical clustering and wetting phenomena in inertial active matter, Commun. Phys. 7, 343 (2024).
- S. Mandal, B. Liebchen, and H. Löwen, Motility-induced temperature difference in coexisting phases, Phys. Rev. Lett. 123, 228001 (2019).
- S. De Karmakar and R. Ganesh, Motility-induced phase separation of self-propelled soft inertial disks, Soft Matter 18, 7301 (2022).
- D. Horvath, C. Slabý, Z. Tomori, A. Hovan, P. Miskovsky, and G. Bánó, Bouncing dynamics of inertial self-propelled particles reveals directional asymmetry, Phys. Rev. E 107, 024603 (2023).
- L. Caprini, A. Ldov, R. K. Gupta, H. Ellenberg, R. Wittmann, H. Löwen, and C. Scholz, Emergent memory from tapping collisions in active granular matter, Commun. Phys. 7, 52 (2024).
- L. Hecht, S. Mandal, H. Löwen, and B. Liebchen, Active refrigerators powered by inertia, Phys. Rev. Lett. 129, 178001 (2022).
- C. Dai, I. R. Bruss, and S. C. Glotzer, Phase separation and state oscillation of active inertial particles, Soft Matter 16, 2847 (2020).
- J. Su, H. Jiang, and Z. Hou, Inertia-induced nucleation-like motility-induced phase separation, New J. Phys. 23, 013005 (2021).
- J. Feng and A. K. Omar, Theory for the anomalous phase behavior of inertial active Brownian particles, Phys. Rev. E 111, L043402 (2025).
- I. Goldhirsch and G. Zanetti, Clustering instability in dissipative gases, Phys. Rev. Lett. 70, 1619 (1993).
- P. Maynar, M. I. García de Soria, and J. J. Brey, Understanding an instability in vibrated granular monolayers, Phys. Rev. E 99, 032903 (2019).
We note that our choice of , related to the Carnahan-Starling expression, is natural for our simulations and theory, which are formulated for hard spheres. Alternative forms of could be considered upon extending the theory to systems with soft interactions.
- A. Baskaran, J. W. Dufty, and J. J. Brey, Transport coefficients for the hard-sphere granular fluid, Phys. Rev. E 77, 031311 (2008).
- N. V. Brilliantov and T. Pöschel, Kinetic Theory of Granular Gases (Oxford University Press, New York, 2010).
The factor in corresponds to the correct choice for comparison with ADSMC simulations.
In general, an out-of-equilibrium passive liquid has and , while and hold for passive systems.
See EM, Physical Units, for a discussion of the Péclet number.
- See Supplemental Material at http://link.aps.org/supplemental/10.1103/mbrl-v75b for details about derivation of the diffusion equation from kinetic theory.
Here, [] stands for the average integer part of its real argument , that is, , where is a random variable that can take value 1 with probability and 0 otherwise ( is the truncated or floor integer part of ).
- L. Hecht, L. Caprini, H. Löwen, and B. Liebchen, How to define temperature in active systems?, J. Chem. Phys. 161, 224904 (2024).
- D. Loi, S. Mossa, and L. F. Cugliandolo, Effective temperature of active complex matter, Soft Matter 7, 3726 (2011).
- A. Akintunde, P. Bayati, H. Row, and S. A. Mallory, Single-file diffusion of active Brownian particles, J. Chem. Phys. 162, 164902 (2025).
- D. Levis and L. Berthier, Clustering and heterogeneous dynamics in a kinetic Monte Carlo model of self-propelled hard disks, Phys. Rev. E 89, 062301 (2014).
- J. U. Klamser, O. Dauchot, and J. Tailleur, Kinetic monte carlo algorithms for active matter systems, Phys. Rev. Lett. 127, 150602 (2021).
- L. Caprini and U. Marini Bettolo Marconi, Bubble phase induced by odd interactions in chiral systems, J. Chem. Phys. 162, 161101 (2025).
- P. Baconnier, O. Dauchot, V. Démery, G. Düring, S. Henkes, C. Huepe, and A. Shee, Self-aligning polar active matter, Rev. Mod. Phys. 97, 015007 (2025).
- A. Puglisi (2026), 10.5281/zenodo.19495697.
- G. A. Bird, Molecular Gas Dynamics and the Direct Simulation of Gas Flows (Oxford University Press, New York, 1994).
- C. Cercignani, R. Illner, and M. Pulvirenti, The Mathematical Theory of Dilute Gases (Springer Science & Business Media, New York, 2013), Vol. 106.