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    Nonequilibrium Structure and Relaxation in Active Microemulsions

    Rakesh Chatterjee1,2, Hui-Shun Kuan1,2,3, Frank Jülicher4,5,6, and Vasily Zaburdaev1,2

    Phys. Rev. Lett. 135, 038401 – Published 15 July, 2025

    DOI: https://doi.org/10.1103/jfm6-8h9s

    Abstract

    Microphase separation is common in active biological systems as exemplified by the separation of RNA- and DNA-rich phases in the cell nucleus driven by the transcriptional activity of polymerase enzymes acting similarly to amphiphiles in a microemulsion. Here we propose an analytically tractable model of an active microemulsion to investigate how the activity affects its structure and relaxation dynamics. Continuum theory derived from a lattice model exhibits two distinct regimes of the relaxation dynamics and is linked to the broken detailed balance due to intermittent activity of the amphiphiles.

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